This seemed to improve performance of My Site and People Picker in SharePoint 2007

– Ran the following commands in sequence:

stsadm -o sync -ListOldDatabases 0

stsadm -o sync -DeleteOldDatabases 0

stsadm –o sync –sweeptiming m:2

stsadm –o sync –synctiming m:2

Please find some of the articles used in this case and some additional information which may help you.

Sync: Stsadm operation (Office SharePoint Server) –

Updates for SharePoint 2010 Products –

Troubleshoot upgrade issues (SharePoint Server 2010)-

Windows PowerShell for SharePoint Server 2010 –

SharePoint 2010 Products administration by using Windows PowerShell –